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Hemoglobin is the most commonly tested iron marker, but itâs also the last to drop.
By the time itâs low, your bodyâs been running on empty for a while.
Donât stop at one test. Ask for a full iron panel to get the full picture.
When I first started looking into iron deficiency, hemoglobin was the only marker I really knew.
It came up in every routine blood test. Itâs what doctors mentioned when I said I was tired. It was what my high school biology class taught me to care about.
So when my hemoglobin came back ânormal,â I figured I was fine.
But I wasnât fine. And I know Iâm not the only one.
My symptoms said something was offâlow energy, low motivation, that ever-present brain fogâbut the labs didnât back me up.
It wasnât until I dug deeper, learning about ferritin, transferrin saturation, and other indicators, that I finally started to piece it together.
By the time hemoglobin drops, the damage has often already been done.
If youâve ever been told âeverything looks normalâ but still donât feel like yourself, this issue is for you.
Let's talk about what hemoglobin can (and canât) really tell you.
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Function: Is Iron Reaching Your Red Blood Cells?
𩸠Hemoglobin: Your Monthly Paycheck
Hemoglobin is the iron-rich protein inside red blood cells that carries oxygen from your lungs to the rest of your body. When it drops, your body isnât delivering enough oxygen to keep up with demand.
But hemoglobin often stays in the ânormalâ range even when your iron is low.
Itâs a lagging indicator. Your body fights to maintain hemoglobin as long as possible, even as other systems start to struggle.
Think of it like a paycheck. You might still be covering your bills, but if your savings (ferritin) are drained and your credit (transferrin saturation) is maxed out, itâs only a matter of time before something gives.
Hemoglobin is what many routine blood tests focus on because itâs used to diagnose anemia. But by the time your levels drop below ~12 g/dL (the common cutoff for women), your iron stores have already been depleted and your transport system has likely been faltering for a while.
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Many routine blood tests check only hemoglobin because itâs the primary marker for diagnosing anemia. But you can be iron-deficient for months or even years before it falls.
If hemoglobin is all your doctor tests, you might not catch iron deficiency early enough.
By the time your hemoglobin drops below the lab reference range (usually ~12 g/dL for women), your iron stores have already been depleted and your transport system has likely been struggling for a while.
Hereâs what happens:
Ferritin drops first â your iron savings start to run out
Transferrin saturation declines â your delivery system begins to struggle
Hemoglobin falls last â your energy, oxygenation, and focus crash
â
Typical reference range for hemoglobin: 12â15.5 g/dL
â ď¸ Deficiency: Below 12 g/dL
đ¨ Severe deficiency (anemia): Below 10 g/dL
In other words:
â Low hemoglobin = Late-stage iron deficiency
Waiting for it to fall means missing early signs your body may already be struggling.
Thatâs why so many women are dismissed or misdiagnosed. Theyâre tired, foggy, and drained, but their hemoglobin looks âfine,â and testing often stops there.
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Start using hemoglobin smarter, not just as your only data point.
đ§ž Donât stop at hemoglobin.
If thatâs all you see on your lab, the pictureâs incomplete. Ask for ferritin and transferrin saturation too.đ Track patterns, not just numbers.
One-off tests can miss slow decline. Keep past results and notice trends.đŹ Use clinical language.
Say: âCan we check for early-stage iron deficiency with ferritin and TSAT?â Specificity helps.â ď¸ Question ânormal.â
A just-barely-normal hemoglobin doesnât rule out deficiency. If symptoms persist, keep digging.

đŹ Whatâs your experience been like with iron testing? Have you ever had symptoms dismissed because your hemoglobin looked ânormalâ?
